Organometallic Compounds
Medchemexpress LLC Tos-PEG3 | 77544-68-4 | 97.0% | 304.36 | 1 G
Tos-PEG3 is a PEG-based PROTAC linker that can be utilized in the synthesis of PROTACs. It can also be used for the synthesis of 3'-aminooxy oligonucleotides solid supports.
- Can be used in the synthesis of PROTACs
- Can be utilized for the synthesis of 3'-aminooxy oligonucleotides solid supports
Medchemexpress LLC Dbco-nhco-peg3-fmoc | 00-00-0 | 96.9% | C42H43N3O7 | 10MG
DBCO-NHCO-PEG3-Fmoc is a DBCO-functionalized PEG3 linker with an Fmoc-protected amine designed for use as a click-chemistry reagent in PROTAC synthesis and bioconjugation. It participates in strain-promoted alkyne-azide cycloaddition (SPAAC) with azide-containing partners, offering modular attachment and improved handling for linker assembly.
- Click-reactive DBCO group enables strain-promoted alkyne-azide cycloaddition (SPAAC).
- Peg3 spacer improves solubility and reduces steric hindrance.
- Fmoc-protected amine allows compatibility with solid-phase and solution-phase synthesis workflows.
- High purity suitable for research applications.
- Stable as powder at -20°C for extended storage and recommended cold storage in solution.
Medchemexpress LLC DBCO-S-S-PEG3-biotin | 1430408-09-5 | 96.9% | 869.12 | 25 MG
DBCO-S-S-PEG3-biotin is a PEG-based PROTAC linker designed for use in the synthesis of PROTACs. It functions as a click chemistry reagent, possessing a DBCO group that facilitates strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing azide groups.
- PEG-based PROTAC linker
- Click chemistry reagent
- Contains a DBCO group for SPAAC reactions
- Used in the synthesis of PROTACs
Medchemexpress LLC 5,8,11-Trioxa-2-azatetradecanedioic acid, 1-(4-cycloocten-1-yl) ester | 2141981-86-2 | MFCD31811538 | 96.0% | 373.44 | 25 MG
TCO-PEG3-acid is a click chemistry reagent that contains a TCO group, which can undergo an inverse electron demand Diels-Alder reaction (iEDDA) with molecules containing Tetrazine groups. It is also a click chemistry PEG linker with a terminal carboxylic acid group. The terminal carboxylic acid is reactive with primary amine groups in the presence of activators to form a stable amide bond.
- Contains a TCO group for inverse electron demand Diels-Alder reaction (iEDDA)
- Reacts with molecules containing Tetrazine groups
- Functions as a click chemistry PEG linker
- Terminal carboxylic acid group
- Forms stable amide bonds with primary amine groups in the presence of activators
Medchemexpress LLC N-(Azido-PEG3)-N-(PEG2-NH-Boc)-PEG3-acid | 2183440-74-4 | 98.1% | C29H55N5O13 | 25 MG
N-(Azido-PEG3)-N-(PEG2-NH-Boc)-PEG3-acid is a PEG-based PROTAC linker utilized in the synthesis of PROTACs. It functions as a click chemistry reagent.
- Can participate in copper-catalyzed azide-alkyne cycloaddition reactions (CuAAc) with alkyne-containing molecules.
- Undergoes strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
- Utilized in the synthesis of PROTACs.
- Enables selective degradation of target proteins through the intracellular ubiquitin-proteasome system.
Medchemexpress LLC Aminooxy-PEG3-acid | 1807540-79-9 | 95.0% | 237.25 | 100 MG
Aminooxy-PEG3-acid is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs. PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
- PEG-based PROTAC linker
- Used in the synthesis of PROTACs
- Exploits the intracellular ubiquitin-proteasome system
- Selectively degrades target proteins
Medchemexpress LLC Aminooxy-PEG3-acid | 1807540-79-9 | 95.0% | 237.25 | 250 MG
Aminooxy-PEG3-acid is a PEG-based PROTAC linker used in the synthesis of PROTACs. These compounds leverage the intracellular ubiquitin-proteasome system to selectively degrade target proteins by connecting an E3 ubiquitin ligase ligand with a target protein ligand. This product is strictly for research use only and not sold to patients.
- PEG-based PROTAC linker
- Used in the synthesis of PROTACs
- Exploits the ubiquitin-proteasome system
- Selectively degrades target proteins
Medchemexpress LLC Azido-PEG5-CH2CO2-NHS | 2144777-77-3 | 97% | C16H26N4O9 | 250 MG
Azido-PEG5-CH2CO2-NHS is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs. It is a click chemistry reagent containing an Azide group, which allows it to undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
- PEG-based PROTAC linker for synthesis
- Click chemistry reagent with azide group
- Undergoes copper-catalyzed azide-alkyne cycloaddition (CuAAc) with alkyne-containing molecules
- Undergoes strain-promoted alkyne-azide cycloaddition (SPAAC) with DBCO or BCN groups
Medchemexpress LLC N-(acid-PEG3)-N-bis(PEG3-azide) | 2182602-17-9 | 98.07% | C25H49N7O11 | 250 MG
N-(acid-PEG3)-N-bis(PEG3-azide) is a PEG-based PROTAC linker utilized in the synthesis of PROTACs. It functions as a click chemistry reagent, containing an Azide group. This allows it to participate in copper-catalyzed azide-alkyne cycloaddition reactions (CuAAc) with molecules that contain Alkyne groups, or in strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
- Composed of two different ligands connected by a linker
- One ligand targets an E3 ubiquitin ligase
- The other targets the protein of interest
- Operates by harnessing the intracellular ubiquitin-proteasome system
- Facilitates the selective degradation of target proteins
- Intended for research use only
Medchemexpress LLC m-PEG5-NH2 | 5498-83-9 | 99.0% | C11H25NO5 | 250 MG
m-PEG5-NH2 is a PEG-based PROTAC linker used in the synthesis of PROTACs. PROTACs are molecules consisting of two distinct ligands connected by a linker: one ligand targets an E3 ubiquitin ligase, and the other targets a specific protein. These molecules function by leveraging the intracellular ubiquitin-proteasome system to selectively degrade target proteins. This product is for research use only and not sold to patients.
- Purity: 99.02%
- Molecular weight: 251.32
- Formula: C11H25NO5
- CAS number: 5498-83-9
- Appearance: Liquid (density: 1.023±0.06 g/cm³)
- Color: Colorless to light yellow
- SMILES: COCCOCCOCCOCCOCCN
- Leverages the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
Medchemexpress LLC M-PEG3-succinimidyl carbonate | 477775-77-2 | 99.4% | C12H19NO8 | 250 MG
m-PEG3-succinimidyl carbonate is a PEG-based PROTAC linker used in the synthesis of PROTACs. PROTACs consist of two different ligands connected by a linker: one binds to an E3 ubiquitin ligase, and the other to the target protein. These molecules function by utilizing the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
- PEG-based PROTAC linker
- Used in the synthesis of PROTACs
- Exploits the intracellular ubiquitin-proteasome system
- Selectively degrades target proteins
- For research use only
Medchemexpress LLC DNP-PEG3-azide | 951671-87-7 | 99.2% | C14H20N6O7 | 25 MG
DNP-PEG3-azide is a PEG-based PROTAC linker crucial for the synthesis of PROTACs. It acts as a click chemistry reagent, featuring an azide group that enables both copper-catalyzed azide-alkyne cycloaddition (CuAAc) with alkyne groups and strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with DBCO or BCN groups. It is a light yellow to yellow viscous liquid with a high purity of 99.18%.
Medchemexpress LLC m-PEG5-Br | 854601-80-2 | 98.0% | C11H23BrO5 | 25 G
m-PEG5-Br is a PEG-based PROTAC linker used in the synthesis of PROTACs. PROTACs are designed to selectively degrade target proteins by utilizing the intracellular ubiquitin-proteasome system. They achieve this by connecting two ligands: one for an E3 ubiquitin ligase and another for the target protein.
- PEG-based PROTAC linker
- Used in the synthesis of PROTACs
- Exploits the ubiquitin-proteasome system
- Selectively degrades target proteins
Medchemexpress LLC Azido-PEG3-C3-OH | 1807512-36-2 | 98.0% | C9H19N3O4 | 250 MG
Azido-PEG3-C3-OH is a PEG-based PROTAC linker designed for use in the synthesis of PROTACs. This click chemistry reagent features an Azide group, facilitating copper-catalyzed azide-alkyne cycloaddition (CuAAc) with alkyne-containing molecules. It also supports strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
- PEG-based PROTAC linker
- Utilized in the synthesis of PROTACs
- Functions as a click chemistry reagent
- Enables copper-catalyzed azide-alkyne cycloaddition (CuAAc)
- Participates in strain-promoted alkyne-azide cycloaddition (SPAAC) reactions
Medchemexpress LLC M-PEG3-Aminooxy | 248275-10-7 | 98.0% | C7H17NO4 | 1 G
m-PEG3-Aminooxy is a PEG-based PROTAC linker utilized in the synthesis of PROTACs. These compounds are designed to exploit the intracellular ubiquitin-proteasome system for the selective degradation of target proteins. PROTACs feature two distinct ligands connected by a linker: one targets an E3 ubiquitin ligase, and the other targets the protein of interest. This product is intended strictly for research purposes and is not for patient use.
- Peg-based PROTAC linker
- Used in the synthesis of PROTACs
- Facilitates selective degradation of target proteins
- For research use only